Fig. 5.

Effect of chronic alcohol exposure on activity of the full-length compared with minimal SLC19A2 and SLC19A3 promoters. Luciferase assays were performed on 266-6 cells transiently transfected with full-length or minimal SLC19A2 (A) and SLC19A3 (B) promoters in pGL3-Basic and exposed chronically to alcohol. Data are reported as relative firefly luciferase activity normalized to Renilla luciferase activity and represent means ± SE of at least 3 independent experiments. *P < 0.01, **P < 0.05.