Fig. 3.

Effect of MJ33 administered with LPS (MJ33-0) or 2 h after LPS (MJ33-2) on cytokine (IL-6, TNF-α) and chemokine (macrophage inflammatory protein 2, MIP-2) release into the BALf at 24 h after LPS. LPS was administered at 1 (LPS-1) or 5 (LPS-5) mg/kg and MJ33 at 0.1 mg/kg. IL-6 (A), TNF-α (B), and MIP-2 (C) are expressed per gram of body weight. Values are means ± SE for n = 5–7. *P < 0.05, **P < 0.01 compared with control (no MJ33 and no LPS) and #P < 0.05, ##P < 0.01 compared with no MJ33 for LPS-1 or LPS-5.