Fig. 7.

Effect of MJ33 administered with LPS (MJ33-0) or 2 h after LPS (MJ33-2) on indices of lung permeability at 24 h after LPS. LPS was administered at 1 (LPS-1) or 5 (LPS-5) mg/kg and MJ33 at 0.1 mg/kg. Total protein in BALf normalized to body weight (A), FITC-dextran 70 measured in the supernatant of lung homogenate and normalized to homogenate protein (B), and lung wet/dry weight ratio (C). Data represent means ± SE for N = 5–7. *P < 0.05, **P < 0.01 compared with control (no MJ33 or LPS) and #P < 0.05, ##P < 0.01 compared with no MJ33 for LPS-1 or LPS-5.