Table 2.
Baseline Characteristics of Older Hospitalized Patients with Chronic Kidney Disease According to Gender
| All (n=1,198) | Men (n=534) | Women (n=664) | p value | |
|---|---|---|---|---|
| Patients (%)a | 100 | 44.5 | 55.5 | — |
| Follow-up, mean (SD), years | 2.1 (1.3) | 1.9 (1.3) | 2.2 (1.3) | <0.001 |
| Age, mean (SD), yearsb | 80.5 (6.8) | 80.2 (7.0) | 80.8 (6.6) | 0.332 |
| Weight, mean (SD), kgb | 64.2 (13.5) | 67.9 (12.2) | 61.2 (13.8) | <0.001 |
| MPI, mean (SD) scoreb | 0.38 (0.2) | 0.35 (0.2) | 0.4 (0.2) | <0.001 |
| eGFR, mean (SD)b | 41.7 (13.0) | 42.4 (12.9) | 41.0 (13.1) | 0.057 |
| ADL, mean (SD) scoreb | 4.4 (2.1) | 4.5 (2.2) | 4.3 (2.1) | 0.008 |
| IADL, mean (SD) scoreb | 3.9 (2.9) | 3.8 (2.7) | 4.1 (3.1) | 0.394 |
| SPMSQ, mean (SD) scoreb | 2.2 (2.3) | 1.9 (2.3) | 2.4 (2.4) | <0.001 |
| Exton–Smith, mean (SD) scoreb | 16.2 (3.0) | 16.4 (3.0) | 15.9 (3.0) | 0.001 |
| CIRS-CI, mean (SD) scoreb | 3.0 (1.7) | 3.0 (1.7) | 2.9 (1.6) | 0.153 |
| MNA, mean (SD) scoreb | 21.1 (5.4) | 21.7 (5.5) | 20.6 (5.2) | <0.001 |
| Drugs number, mean (SD)b | 4.6 (2.8) | 4.7 (3.0) | 4.6 (2.7) | 0.970 |
| Co-morbidity | ||||
| Hypertension (n, %)a | 781 (65.2) | 310 (58.1) | 471 (70.9) | <0.001 |
| Ischemic heart disease (n, %)a | 127 (10.6) | 75 (14.0) | 52 (7.8) | <0.001 |
| Heart Failure (n, %)a | 148 (12.4) | 63 (11.8) | 85 (12.8) | 0.600 |
| Diabetes mellitus (n, %)a | 264 (22.0) | 96 (18.0) | 168 (25.3) | 0.002 |
| Anemia (n, %)a | 441 (36.8) | 187 (35.0) | 254 (38.3) | 0.249 |
| Medications | ||||
| NSAIDs (n, %)a | 84 (7.0) | 31 (5.8) | 53 (8.0) | 0.142 |
| Oral blood glucose lowering drugs (n, %)a | 153 (12.8) | 49 (9.2) | 104 (15.7) | 0.001 |
| Low dose aspirin (n, %)a | 366 (30.6) | 155 (29) | 211 (31.8) | 0.238 |
| ACE inhibitors (n, %)a | 438 (36.6) | 188 (35.2) | 250 (37.7) | 0.294 |
| Angiotensin II antagonists (n, %)a | 233 (19.4) | 81 (15.2) | 152 (22.9) | 0.001 |
| Calcium channel blockers (n, %)a | 214 (17.9) | 82 (15.4) | 132 (19.9) | 0.032 |
| Diuretics (n, %)a | 420 (35.1) | 171 (32.0) | 249 (37.5) | 0.048 |
| Mortality (events/PY, % IR) | 456/2496 (18.3) | 229/1009 (22.7) | 227/1487 (15.3) | <0.001 |
a
Categorical variables.
b
Continuous variables.
MPI, Multidimensional Prognostic Index; eGFR, estimated glomerular filtration rate; ADL, Activities of Daily Living; IADL, Instrumental Activities of Daily Living; SPMSQ, Short-Portable Mental Status Questionnaire; ESS, Exton–Smith Scale; CIRS-CI, Cumulative Illness Rating Scale–Comorbidity Index; MNA, Mini Nutritional Assessment; NSAID, nonsteroidal antiinflammatory drug; ACE, angiotensin-converting enzyme; PY, person-year; IR, incidence rate.