Table 1.

Sequences of AptamiR Constructs and Control Oligonucleotides Used in This Study

Oligonucleotide	Sequence (5′–3′)*
AS1411	GGTGGTGGTGGTTGTGGTGGTGGTGG
c1 AS1411	CCTCCTCCTCCTTCTCCTCCTCCTCC
AptamiR-21	GGTGGTGGTGGTTGTGGTGGTGGTGGTTTGATAAGCT
AptamiR-21sc+	GGTGGTGGTGGTTGTGGTGGTGGTGGTTTTCATACTA
cAptamiR-21	CCTCCTCCTCCTTCTCCTCCTCCTCCTTTGATAAGCT
cAptamiR-21sc+	CCTCCTCCTCCTTCTCCTCCTCCTCCTTTTCATACTA
antimiR-21	GATAAGCT
antimiR-21sc_1	TGATGACA
antimiR-21sc_2	TCATACTA
antimiR-21sc_3	TCTACAAT
antagomir	CAACATCAGTCTGATAAGCTA#
miR-21	UAGCUUAUCAGACUGAUGUUGA

^*Bold indicates phosphorothioate locked nucleic acid (PTO-LNA); underscore, T-Linker phosphodiester linkage; italic, miR-21 seed sequence.

⁺AptamiR-21sc and cAptamiR-21sc are composed of AS1411, T-linker, and the antimiR-21sc_2.

^#all nucleotides 2′ O-Methyl (2′-OMe).