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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Clin Cancer Res. 2014 Feb 3;20(6):1521–1530. doi: 10.1158/1078-0432.CCR-13-2090

Figure 3. Gene Set Enrichment Anaylsis for all top differentially expressed genes.

Figure 3

Each column represents a geneset that is either a key biological process/ pathway/ gene signature from the literature that is enriched among the top 323 DE genes. Each horizontal orange bar represents one of the top DE genes depicted in the sorted order t test score. The black horizontal line separates the genes up-regulated in primary sarcomas (above the line) from those up-regulated in metastases. The occurrence of Pax6, as a stem cell transcription factor, is marked with a green arrow and the distribution of its targets among the DE genes according to mouse ChIP studies [Sansom et al.] is shown with green marks beside the plot.