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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Shock. 2014 Apr;41(4):317–323. doi: 10.1097/SHK.0000000000000121

Figure 5. Summary of complex compartment and treatment-specific inflammatory networks.

Figure 5

Local inflammation in the ascites, arising from the introduction of Endotoxin, causes a rise in both pro- and anti-inflammatory mediators, leading to lung dysfunction. Once established, lung dysfunction perpetuates through a feedback loop with pro-inflammatory mediators. Translocation of pro-inflammatory mediators from ascites to plasma leads to widespread systemic inflammation. Differences between PST and Control are noted.