Table 1.

Clinical and demographical characteristics of study populations.

	GenelD-Central			GenelD-North			GenelD-Central
Characteristics	Ischemic Stroke	Control	p value	Ischemic Stroke	Control	p value	CAD	Control	p value
Subject numbers	903	873	N.A	816	879	N.A	772	873	N.A
Age (years) *	68.3±14.0	45.2±15.1	<1.00E-50	60.2±12.5	52.1±17.0	<1.00E-50	66.1±12.5	45.2±15.1	<1.00E-50
Sex (male%)	61.1	55.7	4.30E-03	57.7	55.9	4.71E-06	69.3	55.7	3.98E-15
Smoking (%)	18.6	6.6	5.98E-26	22.4	17.9	<1.00E-50	26.8	6.6	<1.00E-50
BMI (kg/m2)	24.3±0.3	23.4±2.0	<1.00E-50	24.4±2.7	24.6±1.3	3.89E-04	24.1±1.5	23.4±2.0	1.08E-28
Hypertension (%)	80.1	13.9	<1.00E-50	58.5	26.6	<1.00E-50	69.9	13.9	<1.00E-50
DM	24.4	3.6	<1.00E-50	10.3	13.3	<1.00E-50	25.3	3.6	<1.00E-50
Tch (mmol/1)	4.58±1.01	4.36±0.46	3.53E-17	4.57±0.51	4.36±1.13	1.64E-12	4.40±0.92	4.36±0.46	0.15
TG (mmol/1)	1.49±0.97	1.50±0.50	0.79	1.75±0.78	1.54±1.12	9.80E-11	1.59±1.00	1.50±0.50	0.67
HDL-c (mmol/1)	1.10±0.27	1.19±0.14	1.09E-35	1.20±0.19	1.36±1.24	7.23E-08	1.12±0.27	1.19±0.14	9.51E-19
LDL-c (mmol/1)	2.77±0.80	2.60±0.39	3.14E-15	2.61±0.41	2.40±0.83	1.57E-19	2.62±0.76	2.60±0.39	0.36

The data are presented as the means ± standard deviation or percent;

^*Age for the case group is the age at diagnosis; age for the control group is the age at which the study subject was enrolled;

BMI, body mass index; DM, diabetes; Tch, total cholesterol; TG, triglyceride

HDL-C, high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol;