. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: J Pediatr. 2014 Jan 10;164(4):775–780. doi: 10.1016/j.jpeds.2013.11.038

Table 1.

Clinical associations with large HRC index spikes not associated with surgical procedures, based on randomization to HRC display or non-display

	HRC Display (89 spikes)	Non-Display (102 spikes)	p=
Infants with spikes, n (% of all infants)	47 (34.1%)	47 (34.6%)	1.0
Spikes per infant	1.9 ± 1.3	2.2 ± 1.8	0.40
Gestational age, weeks	25.8 ± 2.3	25.8 ± 2.0	0.64
Birth weight, grams	831 ± 238	825 ± 220	0.85
Day of age at spike, median (IQR)	33 (19–55)	26 (16–41)	0.05
Antibiotics started	63/89 (71%)	45/102 (44%)	<0.001
Sepsis, blood culture positive	10	10	0.81
Sepsis, clinical	22	14	0.06
Sepsis ruled out	19	9	0.02
Urinary tract infection	5	4	0.74
Necrotizing enterocolitis	5	6	1.00
Other infection	2	2	1.00
Total antibiotic days during NICU stay	31.4 ± 23.9	25.7 +/− 20.3	0.21