Table 2.
Mean (SD) HPA Activity by Group
| Variable | Total Sample (N = 104) | PTSD+/− | MDD+/− | Comorbidity Classification | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PTSD+ (N = 68) | PTSD− (N = 36) | F-test (df) p-value |
MDD+ (N = 55) | MDD− (N = 49) | F-test (df) p-value |
No PTSD or MDD (N = 24) | MDD Only (N = 12) | PTSD Only (N = 25) | PTSD & MDD (N = 43) | F-test (df) p-value |
||
| Waking | 11.95 (7.25) | 11.69 (7.66) | 12.45 (6.50) | .74 (8,95) .39 |
10.25 (6.06) | 13.86 (8.04) | 5.11 (8,95) .03 |
13.99 (7.12) | 9.38 (3.62) | 13.73 (8.98) | 10.50 (6.60) | 1.69 (10,93) .18 |
| AUCg | 833.88 (406.40) | 858.39 (449.30) | 787.59 (310.22) | 1.14 (8,95) .29 |
816.28 (413.50) | 853.63 (401.62) | .06 (8,95) .80 |
825.03 (352.23) | 712.72 (193.97) | 881.10 (449.56) | 845.19 (453.94) | .58 (10,93) .63 |
| AUCi | 116.81 (317.37) | 157.23 (339.24) | 40.46 (258.74) | 6.75 (8,95) .01 |
201.05 (319.35) | 22.24 (290.08) | 8.44 (8,95) .01 |
−14.17 (271.42) | 149.72 (198.60) | 57.20 (308.38) | 215.38 (346.16) | 3.62 (10,93) .02 |
Waking = waking cortisol (nmol/dl); AUCg = Area Under the Curve with Respect to Ground (nmol/dl); AUCi = Area Under the Curve with Respect to Increase (nmol/dl).
Note: All F-values control for age, chronicity, minority status, anti-anxiety medication, other Anxiety Disorders, Bipolar Spectrum Disorder and time between waking and first saliva sample.