Skip to main content
. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Mol Cancer Res. 2013 Dec 27;12(3):359–369. doi: 10.1158/1541-7786.MCR-13-0526

Figure 1. Ectopic expression of RBM24 suppresses p63 expression.

Figure 1

(A) Sequence similarity between human RBM38 and RBM24. The RNP1 and RNP2 submotifs are shown in boxes. (B–D) Ectopic expression of RBM24 inhibits ΔNp63α expression. ME180 (B), HaCaT (C), and MCF10A (D) cells were transiently transfected with a control vector or a vector expressing HA-tagged RBM24 for 48 h, and the level of HA-tagged RBM24, ΔNp63α, and actin was determined by Western blot analysis. The level of ΔNp63α protein was normalized to that of actin and arbitrary set as 1.0 in control cells. The relative fold changes were shown below each lane. (E) RBM24 inhibits TAp63α expression. MIA-PaCa2 cells was transiently transfected with a control vector or a vector expressing HA-tagged RBM24 for 48 h, followed by Western blot analysis to determine the level of HA-tagged RBM24, TAp63α, and actin. The level of TAp63α protein was normalized to that of actin and arbitrary set as 1.0 in control cells. The relative fold changes were shown below each lane.