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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Clin Pharmacokinet. 2014 Apr;53(4):361–371. doi: 10.1007/s40262-013-0122-1

Table 3.

Population Estimation Results for LPVf Model

Parametera Mean (%RSE)b IIV CV% (%RSE)b
CLLPVf (L/h) 596. (9.61) 41.0 (17.2)
VLPVf (L) 6370 (15.9) 52.6 (26.3)
kaLPVf (1/h) 0.884 (47.5) 120. (95.6)
Tlag,f (h) 1.05 (15.0) 45.1 (48.8)
a

IIV: Inter-individual variability; CV: coefficient of variation; RSE: relative standard error.

b

CLLPVf: free LPV (LPVf) clearance; VLPVf : LPVf distribution volume; kaLPVf: absorption rate constant; Tlag,f: absorption lag time.