Table 3.
Parametera | Mean (%RSE)b | IIV CV% (%RSE)b |
---|---|---|
CLLPVf (L/h) | 596. (9.61) | 41.0 (17.2) |
VLPVf (L) | 6370 (15.9) | 52.6 (26.3) |
kaLPVf (1/h) | 0.884 (47.5) | 120. (95.6) |
Tlag,f (h) | 1.05 (15.0) | 45.1 (48.8) |
IIV: Inter-individual variability; CV: coefficient of variation; RSE: relative standard error.
CLLPVf: free LPV (LPVf) clearance; VLPVf : LPVf distribution volume; kaLPVf: absorption rate constant; Tlag,f: absorption lag time.