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Effect of S1P1 agonist on SKI II-evoked decrease in cell viability. Cells were incubated with 10 µM SKI II in the presence of 5 µM SEW2871 for 24 h. Cell viability was spectrophotometrically determined using the MTT assay. Data represent the mean value ± SEM for three separate experiments carried out in triplicate. ***p < 0.001 versus corresponding control, using one-way ANOVA followed by Bonferroni’s Multiple Comparison Test
