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. 2014 Mar 12;144(3):607–614. doi: 10.1007/s10549-014-2902-1

Table 1.

Observed breast cancers in total series and subgroups based on family history in woman <50 years, in women 50–59 years, and in total series compared to expected compared to population

Groups
(Number in group)
Ages Observation years Observed breast cancers Expected breast cancers χ 2

Total series

(n = 3,161)

25–49 17,873 36 16.8 21.9**
50–59 6,935 28 17.2 6.8**
25–59 24,808 64 34.0 26.4**

Four breast cancer cases or more in family

(n = 314)

25–49 1,626 5 1.6 7.2**
50–59 836 4 2.1 1.8
25–59 2,462 9 3.7 7.7**

Two breast cancer cases = <55 years or more in family

(n = 865)

25–49 5,085 15 4.6 23.1**
50–59 1,819 11 4.5 9.3**
25–59 6,904 26 9.2 31.0**

One case only in family and that case = <50 years

(n = 735)

25–49 4,669 6 4.2 0.8
50–59 1,474 5 3.7 0.5
25–59 6,143 11 7.8 1.3
Breast and ovarian cancer in family 25–49 4,370 7 4.1 2.0
50–59 1,890 7 4.7 1.1
25–59 6,260 14 8.7 3.1

(no result had 0.05<p<0.01), ** p < 0.01