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. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: Clin Cancer Res. 2014 Feb 15;20(4):782–790. doi: 10.1158/1078-0432.CCR-13-0583

Table 1.

TNBC subtyping predictions for TCGA primary breast tumors

TNBC Subtypea # Samples (Percentage) Median DFS (Months)b Median OS (Months)b
BL1 27 (17%) 20.1 21.1
BL2 12 (7%) 12.5 8.4
IM 30 (18%) 22.7 24.8
M 39 (24%) 9.1 9.5
MSL 10 (6%) 13.9 20.9
LAR 14 (9%) 4.4 5.7
UNC 31 (19%) 22.0 24.9

All TNBC 163 (100%) 11.8 15.2

Abbreviations: DFS, disease free survival; OS, overall survival.

a

TNBC subtype predictions for the TCGA primary tumors were made using RSEM genes normalized (upper quartile count = 1,000) RNA-seq abundance estimates (20130606 Firehose BRCA stddata run). TNBC cases were identified as previously described (8). Samples were filtered on ER, PR, and HER2 mRNA expression to identify TNBC tumors and outliers were removed after principal component analysis. The TNBCtype tool (10) was used to make TNBC subtype predictions for the 163 TNBC samples.

b

Survival data for TCGA TNBC cases was obtained from the cBioPortal (www.cbioportal.org) on 12-19-2013.