Samples were collected within scheduled windows, plus additional scavenged samples as available. For this graph, collection times were clustered as follows to obtain mean values: 0 h (baseline) = obtained prior to infusion; 0.3 h (end of infusion) = 0–2 h post-infusion; 4 h = 2–6 h post-infusion; 8 h = 6–10 h post-infusion; 12 h = 10–14 h post-infusion; 24 h= 14–30 h post-infusion; 36 h = 30–42 h post-infusion; 48 h = 43–60 h post-infusion; 72 h = 60–82 h post-infusion; 96 h = >82 h post-infusion. Square = placebo, circle = 60mg/kg, triangle= 120mg/kg, vertical bar = ± 1 SD.