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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Ann Biomed Eng. 2013 Dec 3;42(2):243–259. doi: 10.1007/s10439-013-0952-x

Figure 4. Iron oxide nanoparticle linked immunosorbent assay.

Figure 4

(a) Nanocrystal amplification. The nanocrystal conjugated with the probe is dissolved by acid into individual metal atoms which are converted to chromophores through a stoichiometric reaction. Signal amplification is fully determined by the total number of atoms in the nanocrystals bound to a single target molecule. (b) VCAM-1 in the lysate of LPS-stimulated HUVEC was quantified with a sandwich ILISA. Mean ± standard deviation of three measurements is plotted. (c) Instrument-free distinction of factor-X deficient vs. normal human plasma. Factor X in human plasma was detected with a sandwich ILISA.