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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Sep 23;1842(8):1219–1231. doi: 10.1016/j.bbadis.2013.09.010

Figure 5. Aβ accumulation and cognitive decline timelines.

Figure 5

Before notable cognitive decline commences, Aβ accumulation initiates, accelerates, peaks, and decelerates. By the time cognitive decline begins, Aβ accumulation virtually has virtually ceased.