TABLE 1.
Sociodemographic and Clinical Characteristics at ART Initiation
| Baseline Characteristics | Lesotho (n = 789) | Malawi (n = 880) | Swaziland (n = 637) | Total (N = 2306) | |
|---|---|---|---|---|---|
| Sociodemographic | |||||
| Age, median (IQR), y | 3.6 (1.4–7.4) | 2.4 (1.1–6.1) | 3.8 (1.5–7.6) | 3.1 (1.4–7.1) | |
| Gender, female | 399 (51.0%) | 411 (46.7%) | 299 (46.9%) | 1109 (48.2%) | |
| Clinical | |||||
| WHO Stage | |||||
| I | 175 (22.2%) | 86 (9.8%) | 62 (9.7%) | 323 (14.0%) | |
| II | 94 (11.9%) | 121 (13.7%) | 154 (24.2%) | 369 (16.0%) | |
| III | 340 (43.1%) | 540 (61.4%) | 277 (43.5%) | 1157 (50.2%) | |
| IV | 180 (22.8%) | 132 (15.0%) | 137 (21.5%) | 449 (19.5%) | |
| Missing | 0 (0.0%) | 1 (0.1%) | 7 (1.1%) | 8 (0.3%) | |
| Immunosuppression | |||||
| None | 50 (7.8%) | 76 (8.6%) | 49 (6.2%) | 175 (7.6%) | |
| Mild | 74 (11.6%) | 61 (6.9%) | 79 (10.0%) | 214 (9.3%) | |
| Advanced | 114 (17.9%) | 122 (13.9%) | 171 (21.7%) | 407 (17.6%) | |
| Severe | 389 (61.1%) | 595 (67.6%) | 486 (61.6%) | 1470 (63.7%) | |
| Missing | 10 (1.6%) | 26 (3.0%) | 4 (0.5%) | 40 (1.7%) | |
| CD4 Values | |||||
| Age <5 y: CD4%, median (IQR) | 15 (11–20) | 15 (10–19) | 14 (10–18) | 15 (10–19) | |
| Age ≥5 y: CD4 cell count, median (IQR) | 255 (111–351) | 235 (113–429) | 264 (108–416) | 253 (111–398) | |
| Nutritional status | |||||
| Normal | 399 (50.6%) | 639 (72.6%) | 387 (60.7%) | 1425 (61.8%) | |
| Mild malnutrition | 159 (20.2%) | 48 (5.5%) | 107 (16.8%) | 314 (13.6%) | |
| Moderate malnutrition | 140 (17.7%) | 74 (8.4%) | 75 (11.8%) | 289 (12.5%) | |
| Severe malnutrition | 71 (9.0%) | 36 (4.1%) | 47 (7.4%) | 154 (6.7%) | |