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. 2012 Sep;130(3):e591–e599. doi: 10.1542/peds.2011-1187

TABLE 4.

Immune Status Improvement at 12 Months (N = 1687)

Immune Status Improvement
n Improved n (%), n = 1526 Unadjusted OR (95% CI) Adjusted OR (95% CI)a
Country
 Swaziland 484 452 (93.4%) Reference Reference
 Malawi 555 496 (89.4%) 0.60 (0.38–0.93) 0.61 (0.38–0.96)
 Lesotho 648 578 (89.2%) 0.59 (0.38–0.90) 0.59 (0.38–0.92)
Gender
 Male 882 800 (90.7%) Reference
 Female 799 720 (90.1%) 0.93 (0.68–1.29)
 Missing 6 6 (100.0%)
Age
 <6 mo 66 52 (78.8%) 0.36 (0.19–0.68) 0.34 (0.17–0.65)
 6 to <12 mo 193 165 (85.5%) 0.58 (0.36–0.91) 0.58 (0.37–0.93)
 12 to <36 mo 505 468 (92.7%) 1.23 (0.82–1.85) 1.26 (0.83–1.89)
 ≥36 mo 923 841 (91.1%) Reference Reference
PMTCT
 No PMTCT 1086 995 (91.6%) Reference
 PMTCT 209 182 (87.1%) 0.62 (0.39–0.97)
 Missing 392 349 (89.0%)
WHO stage
 I 227 210 (92.5%) Reference Reference
 II 282 257 (91.1%) 0.83 (0.44–1.58) 0.59 (0.30–1.15)
 III 872 791 (90.7%) 0.79 (0.46–1.36) 0.62 (0.35–1.10)
 IV 306 268 (87.6%) 0.57 (0.31–1.04) 0.46 (0.25–0.85)
Nutritional status at ART initiation
 Normal 1076 981 (91.2%) Reference
 Mild malnutrition 260 236 (90.8%) 0.95 (0.60–1.52)
 Moderate malnutrition 210 187 (89.0%) 0.79 (0.49–1.27)
 Severe malnutrition 97 88 (90.7%) 0.95 (0.46–1.94)
 Missing 44 34 (77.3%)

OR, odds ratio.

a

Adjusted for country, age, and WHO stage. Patients who died in the first 12 mo on ART excluded.