Figure 2.

Use of therapeutic vaccination to achieve a functional cure. Vaccination of patients on a 3 drug HAART regimen (yellow, blue and green rectangles) may allow the subsequent control of viremia after cessation of HAART to levels seen in ES. Because the mechanisms for control of HIV-1 replication in ES are not completely clear, the nature of the therapeutic vaccine is still uncertain. However, the stimulation of HIV-1- specific CTL responses is likely to be important.