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Inhibitory effects of components from gymnema leaves on TPA-induced inflammatory ear oedema.
| Component | ID50 | 95% CI |
|---|---|---|
| (nmol/ear) | ||
| Gymnemagenin (2) | 555 | 417–739 |
| 28-Acetyl-21-tigloylgymnemagenin (3) | 49.7 | 38.3–64.7 |
| Gymnemic acid III (4) | 212 | 160–281 |
|
| ||
| Indomethacina | 908 | 755–1092 |
| Hydrocortisonea | 69.1 | 64.3–75.4 |
ID50: 50% inhibitory dose. 95% CI: 95% confidence intervals. aReference compound.
