Grade of recommendation
A
|
a. Postoperative radiotherapy after breast-conserving surgery
for DCIS lowers the rate of invasive and non-invasive local
recurrences without any demonstrable effect on overall
survival. |
Level of evidence
1a
|
(Bijker N et al. 2006; Clarke M et al. 2005; Cochrane:
Goodwin A et al. 2009; Cutuli B et al. 2002; Cuzick J et al.
2011; EBCTCG: Correa C et al. 2010; Emdin SO et al. 2006;
Holmberg L et al. 2008) |
Grade of recommendation
A
|
b. The absolute risk reduction in the local recurrence rate
by radiotherapy after breast-conserving surgery for DCIS
depends on individual factors. |
Level of evidence
1b
|
(Baxter NN et al. 2005; Boyages J et al. 1999; Cochrane:
Goodwin A et al. 2009; Cuzick J et al. 2011; EBCTCG: Correa
C et al. 2010; Houghton J et al. 2003; Omlin A et al. 2006;
Shelley W et al. 2006; Smith BD et al. 2006) |