| Surg-1 | Tumor resection |
|---|---|
| a. Tumor excision with a negative resection margin (R0 status) is the basis of therapy for all non-advanced breast carcinomas. | |
| GCP | (Blichert-Toft M et al. 1998; Renton SC et al. 1996) |
| b. The resection margin status has a prognostic effect in invasive breast carcinoma. There is a significant relationship between the resection margin status (positive vs. close vs. negative) and the local recurrence rate. | |
| Level of evidence 3a | (Houssami N et al. 2010) |
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