| Adj-2 | Pharmacotherapy of the primary disease |
|---|---|
| Grade of recommendation A | Pharmacotherapy of the primary disease is undertaken before or after surgery in the form of chemotherapy, endocrine therapy, anti-HER2 antibody therapy or a combination or sequence of these different forms. |
| Level of evidence 1a | (EBCTCG 2005; NCCN 2006) |
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