Figure 2. Patient disposition and study populations.

*Includes patients meeting seizure-related exit criteria. For patients meeting exit criteria, the primary reason for discontinuation was recorded as “insufficient clinical response” unless the patient also experienced an adverse event (AE) requiring discontinuation at the same time, in which case the primary reason for discontinuation was reported as the AE. **Other reasons for discontinuation included loss to follow-up, no longer willing to participate, protocol violation, pregnancy, or other.