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. Author manuscript; available in PMC: 2014 Mar 24.
Published in final edited form as: Immunol Rev. 2012 Nov;250(1):49–60. doi: 10.1111/imr.12004

Fig. 7. Replacement of TCRα Y29 with an alanine in mice expressing a Vα4-containing TCRα as their only TCRα chain reduces positive selection of T cells.

Fig. 7

Mice were produced as described in Fig. 5 except that they expressed a single TCRα that of B3K508 (109) and any possible TCRβ. Thymi were analyzed for the numbers of CD4+ and CD8+ T cells they contained. Data shown are the means and SEMs of at least three mice of each type.