Table 4.

Summary statistics for the hybrid design, greedy design, and non-adaptive balanced allocation, for the (3-dose, 2-schedule) trial. The “balanced” method assigns 12 patients to each (schedule, dose) pair and does only one posterior computation, at the end of the trial. The number in parentheses after each R_select is the percentage of times the trial is stopped with no (schedule, dose) selected. Because scenarios 7 (too toxic) and 8 (too inefficacious) have no acceptable treatments, the R_select values are less relevant and thus are shown with a gray background.

Scenario	Hybrid		Greedy		Balanced
	Rselect	Rtreat	Rselect	Rtreat	Rselect	Rtreat
1	0.82 (1)	0.54	0.78 (1)	0.45	0.85 (0)	0.50
2	0.85 (1)	0.75	0.85 (1)	0.84	0.85 (0)	0.51
3	0.81 (1)	0.54	0.78 (1)	0.48	0.83 (0)	0.50
4	0.80 (1)	0.69	0.80 (0)	0.77	0.80 (0)	0.51
5	0.74 (1)	0.54	0.65 (1)	0.48	0.77 (0)	0.40
6	0.76 (2)	0.62	0.75 (3)	0.62	0.77 (0)	0.55
7	0.87 (100)	0.81	1.00 (100)	0.83	0.94 (98)	0.50
8	0.54 (96)	0.54	0.54 (96)	0.59	0.35 (72)	0.50