Table 3.
Regimen | Time to progression (months) |
Response (3 months) |
Response (6 months) |
Status | Death from stopping regimen (months) |
Follow-up (months) |
|
---|---|---|---|---|---|---|---|
Patient | |||||||
1 | BIT | 6 | SD | PD | Dead | 2 | |
2 | BIT | 14 | PR | CR | AWDa | N/A | 20 |
3 | BIT | N/A | PR | PR | AWD PF | N/A | 15 |
4 | BIT | 11 | PR | CR | Dead | 2 | |
5 | BI | 6 | PR | PD | Dead | 4 | |
6 | BIT | N/A | SD | SD | AWD PF | N/A | 55 |
7 | BI | 18 | PR | CR | Dead | 3 | |
8 | BITV | 10 | PR | PR | Dead | 3 | |
9 | BITV | 4 | SD | PD | Dead | 2 |
Bl bevacizumab+irinotecan, BIT BI+temozolomide, BITV BIT+vincristine, N/A not applicable, AWD alive with disease, CR complete response, PD progressive disease, PF progression free, PR partial response, SD stable disease
Progressed after 14 months of salvage therapy, but remains AWD for 18 months