Figure 1.

Intestinal tumor formation in ApcMin/+ mice with cell‐type specific Cox2 gene deletions. (Panel A) The Cox2 gene was deleted in myeloid cells of ApcMin/+Cox2ΔM mice. Intestinal tumors in ApcMin/+Cox2ΔM mice and littermate control ApcMin/+ mice were counted at 150 days of age. (Panel B) The Cox2 gene was deleted in intestinal epithelial cells of ApcMin/+Cox2ΔE mice. Intestinal tumors in ApcMin/+Cox2ΔE mice and control littermate ApcMin/+ mice were counted at 180 days of age. p‐values for the Cre effect were computed from the two‐way ANOVA models. Means ± S.E. are shown.