Table 1. Other outcome measures of the serotonin transporter genotype by stress environment (control or inescapable shocks) experiment.
Outcome Measure |
Effect | Genotype | Treatment | n | Mean | SE | ||
---|---|---|---|---|---|---|---|---|
Genotype | Stress | G × E interaction |
||||||
Ambulatory distance in OF | ** | * | ns | WT | Control | 24 | 974 | 85 |
Inescapable Shock | 26 | 860 | 107 | |||||
Het | Control | 27 | 980 | 75 | ||||
Inescapable Shock | 27 | 718 | 92 | |||||
KO | Control | 24 | 719 | 108 | ||||
Inescapable Shock | 25 | 531 | 101 | |||||
Percent distance in OF center | # | ** | ns | WT | Control | 25 | 1.33 | 0.52 |
Inescapable Shock | 26 | 2.78 | 0.81 | |||||
Het | Control | 26 | 0.69 | 0.19 | ||||
Inescapable Shock | 25 | 2.43 | 0.83 | |||||
KO | Control | 23 | 0.26 | 0.12 | ||||
Inescapable Shock | 23 | 1.13 | 0.46 | |||||
Bite latency in NSF (s) | *** | ns | * | WT | Control | 21 | 59.3 | 8.3 |
Inescapable Shock | 22 | 66.0 | 9.6 | |||||
Het | Control | 17 | 76.4 | 12 | ||||
Inescapable Shock | 19 | 102 | 20 | |||||
KO | Control | 21 | 194 | 28 | ||||
Inescapable Shock | 20 | 129 | 20 | |||||
5 min pellet consumption (g) | ns | ns | ns | WT | Control | 20 | .135 | .015 |
Inescapable Shock | 20 | .165 | .018 | |||||
Het | Control | 18 | .128 | .023 | ||||
Inescapable Shock | 19 | .111 | .025 | |||||
KO | Control | 20 | .100 | .021 | ||||
Inescapable Shock | 20 | .140 | .011 | |||||
Percent weight lost in NSF | ns | ns | ns | WT | Control | 17 | 8.48 | .68 |
Inescapable Shock | 17 | 8.58 | .62 | |||||
Het | Control | 15 | 8.30 | .78 | ||||
Inescapable Shock | 17 | 8.20 | .72 | |||||
KO | Control | 18 | 7.50 | .96 | ||||
Inescapable Shock | 17 | 7.32 | .76 | |||||
Immobility min 3–7 in FST | *** | ns | ns | WT | Control | 27 | 148 | 13 |
Inescapable Shock | 26 | 158 | 11 | |||||
Het | Control | 26 | 139 | 11 | ||||
Inescapable Shock | 27 | 157 | 10 | |||||
KO | Control | 25 | 214 | 9 | ||||
Inescapable Shock | 26 | 214 | 11 |
p < .05,
p < .01,
p < .0001,
p < .1,
"ns" not significant.
In addition, for each outcome measure, group results including number of subjects, mean, and standard error of the group are indicated.
Abbreviations: KO – knockout with no functional serotonin transporter, Het – one functional and one disrupted 5HTT allele, WT – wild-type, OF – Open Field, NSF – Novelty Suppressed Feeding, FST – Forced Swim Test.