Table 1. Other outcome measures of the serotonin transporter genotype by stress environment (control or inescapable shocks) experiment.
For each outcome measure (named in the first column) there is an indication whether each effect was significant: genotype, stress, and interaction of stress and genotype.
| Outcome Measure |
Effect | Genotype | Treatment | n | Mean | SE | ||
|---|---|---|---|---|---|---|---|---|
| Genotype | Stress | G × E interaction |
||||||
| Ambulatory distance in OF | ** | * | ns | WT | Control | 24 | 974 | 85 |
| Inescapable Shock | 26 | 860 | 107 | |||||
| Het | Control | 27 | 980 | 75 | ||||
| Inescapable Shock | 27 | 718 | 92 | |||||
| KO | Control | 24 | 719 | 108 | ||||
| Inescapable Shock | 25 | 531 | 101 | |||||
| Percent distance in OF center | # | ** | ns | WT | Control | 25 | 1.33 | 0.52 |
| Inescapable Shock | 26 | 2.78 | 0.81 | |||||
| Het | Control | 26 | 0.69 | 0.19 | ||||
| Inescapable Shock | 25 | 2.43 | 0.83 | |||||
| KO | Control | 23 | 0.26 | 0.12 | ||||
| Inescapable Shock | 23 | 1.13 | 0.46 | |||||
| Bite latency in NSF (s) | *** | ns | * | WT | Control | 21 | 59.3 | 8.3 |
| Inescapable Shock | 22 | 66.0 | 9.6 | |||||
| Het | Control | 17 | 76.4 | 12 | ||||
| Inescapable Shock | 19 | 102 | 20 | |||||
| KO | Control | 21 | 194 | 28 | ||||
| Inescapable Shock | 20 | 129 | 20 | |||||
| 5 min pellet consumption (g) | ns | ns | ns | WT | Control | 20 | .135 | .015 |
| Inescapable Shock | 20 | .165 | .018 | |||||
| Het | Control | 18 | .128 | .023 | ||||
| Inescapable Shock | 19 | .111 | .025 | |||||
| KO | Control | 20 | .100 | .021 | ||||
| Inescapable Shock | 20 | .140 | .011 | |||||
| Percent weight lost in NSF | ns | ns | ns | WT | Control | 17 | 8.48 | .68 |
| Inescapable Shock | 17 | 8.58 | .62 | |||||
| Het | Control | 15 | 8.30 | .78 | ||||
| Inescapable Shock | 17 | 8.20 | .72 | |||||
| KO | Control | 18 | 7.50 | .96 | ||||
| Inescapable Shock | 17 | 7.32 | .76 | |||||
| Immobility min 3–7 in FST | *** | ns | ns | WT | Control | 27 | 148 | 13 |
| Inescapable Shock | 26 | 158 | 11 | |||||
| Het | Control | 26 | 139 | 11 | ||||
| Inescapable Shock | 27 | 157 | 10 | |||||
| KO | Control | 25 | 214 | 9 | ||||
| Inescapable Shock | 26 | 214 | 11 | |||||
p < .05,
p < .01,
p < .0001,
p < .1,
"ns" not significant.
In addition, for each outcome measure, group results including number of subjects, mean, and standard error of the group are indicated.
Abbreviations: KO – knockout with no functional serotonin transporter, Het – one functional and one disrupted 5HTT allele, WT – wild-type, OF – Open Field, NSF – Novelty Suppressed Feeding, FST – Forced Swim Test.