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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Cancer Res. 2013 Nov 26;74(2):471–483. doi: 10.1158/0008-5472.CAN-13-2134-T

Figure 5. Effects of Tgfbr2 knockout in BM-derived cells on existing SmoM2-derived tumors.

Figure 5

A shows a diagram of the experimental design. In brief, SmoM2 was first induced by tamoxifen before BM transplantation. Six weeks later, skin biopsies were collected for histology analyses. B shows H&E staining of skin sections with wild type (top panel) or Tgfbr2 deficiency (bottom panel) in the BM-derived cells after SmoM2 induction. C shows the percentage of tumor areas in different groups of mice.