Table 1.
Lupus patients versus controls*
| Pts (N=119) | Control (N=71) | P value | |
|---|---|---|---|
| Age (yr) | 42.6 (12.4) | 41.3 (11.9) | 0.49 |
| Caucasian (%) | 41 | 47 | 0.81 |
| Postmenopausal (%) | 38 | 31 | 0.47 |
| Female (%) | 91 | 91 | 0.95 |
| Body-mass index | 25.9 (6.3) | 24.8 (5.3) | 0.29 |
| Plaque (%) | 43 | 17 | 0.0002 |
| IMT (mm) | 0.59 (0.19) | 0.54 (0.11) | 0.03 |
| Current Smoker (%) | 9.7 | 15.4 | 0.33 |
| Hypertension (%) | 37 | 12 | 0.0006 |
| Diabetes (%) | 3 | 2 | 1.00 |
| Systolic blood pressure | 117.7 (19.6) | 113.2 (16.9) | 0.13 |
| Diastolic blood pressure | 74.2 (11.5) | 73.6 (11.0) | 0.74 |
| Total Cholesterol (mg/dl) | 177.2 (38.6) | 189.0 (33.4) | 0.04 |
| HDL Cholesterol (mg/dl) | 57.2 (18.8) | 63.6 (17.3) | 0.03 |
| LDL Cholesterol (mg/dl) | 100.0 (31.0) | 107.0 (28.6) | 0.13 |
| Triglycerides (mg/dl) | 101.8 (63.8) | 91.6 (55.6) | 0.27 |
| Homocysteine (μM) | 10.2 (4.0) | 9.2 (2.7) | 0.07 |
| Dyslipidemia** (%) | 40.3 | 38.0 | 0.76 |
| Cardio CRP (% >10 mg/L) | 12 | 3 | 0.05 |
| Cardio CRP (% >3 mg/L) | 36 | 23 | 0.09 |
| anti-ds DNA (%) | 0.46 | 0 | <0.0001 |
| C3 (mg/dl) | 94.7 (27.6) | 111.2 (27.5) | 0.0002 |
| C4 (mg/dl) | 18.5 (9.9) | 25.3 (8.2) | <0.0001 |
| sE-selectin (ng/ml) | 64.1 (45.3) | 36.5 (16.2) | <0.0001 |
| CECs (cells/ml) | 19.4 (14.7) | 3.8 (3.3) | <0.0001 |
| Genotype EPCR (%) | 26 | 17 | 0.46 |
| sEPCR (ng/ml) | 237.3 (158.0) | 232.2 (99.2) | 0.79 |
| Adiponectin (μg/ml) | 16.0 (9.2) | 11.4 (6.1) | 0.0001 |
*
For continuous variables, mean value (S.D.)
**
Dyslipidemia was calculated as previously reported [5]