Table 1.
Brief summary of the major findings.
Samples | Results |
---|---|
Distant metastases | Genetic diversity overall is high especially in TNBCs |
Genetic diversity indices are similar regardless of the probe used | |
Two lesions in the same patients have significantly different diversity in some cases and some probes | |
In some cases genetic diversity differs between the two metastatic lesions only in some cell types | |
Two lesions in the same patient are frequently phenotypically distinct except in TNBC cases | |
Matched primary tumors and lymph node metastases | Genetic diversity overall is lower than in distant metastases, especially true in TNBCs |
Genetic diversity indices are similar regardless of the probe used | |
Genetic diversity is significantly different in most cases and most probes | |
Diversity for 8q24 is lower in some primary TNBCs and higher in the lymph node metastasis | |
Diversity for 8q24 is higher in some primary Her2+ tumors and lower in the lymph node metastasis | |
Primary and matched lymph node metastasis are phenotypically more similar in most cases |