Table 2.
Clinicopathologic features of HIV-positive and HIV-negative patients with anal cancer
| HIV+ (N =12) | HIV− (N =30) | P value | |||
|---|---|---|---|---|---|
| Stage | N | % | N | % | |
| I | 2 | 17 % | 5 | 17 % | 0.34a |
| II | 3 | 25 % | 13 | 43 % | |
| III | 5 | 42 % | 8 | 27 % | |
| IV | 1 | 8 % | 3 | 10 % | |
| Unknown | 1 | 8 % | 1 | 4 % | |
| Outcome | |||||
| Tumor recurrence + | 6 | 50 % | 7 | 23 % | 0.09b |
| Tumor recurrence − | 6 | 50 % | 23 | 77 % | |
| Histologic tumor type | |||||
| Non-keratinizing | 4 | 33 % | 23 | 77 % | 0.008c |
| Keratinizing | 8 | 67 % | 7 | 23 % | |
a
Pearson’s chi-square test for difference in local tumors (stage I/II) and advanced tumors (stage III/IV) between HIV-positive and HIV-negative patients
b
Pearson’s chi-square test for difference in tumor recurrence between HIV-positive and HIV-negative patients
c
Pearson’s chi-square test for difference in tumor histologic type distribution between HIV-positive and HIV-negative patients