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. 2014 Mar 24;9(3):e92729. doi: 10.1371/journal.pone.0092729

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© 2014 Cambien et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Volume-rendered, fused SPECT/CT images in anterior and lateral views demonstrating the thyroid lobes (red) and the salivary glands (blue-green), 60 minutes after ^99mTcO₄ ⁻ administration. (B) Kinetics of ^99mTcO₄ ⁻ activity in the thyroids of four Balb/c mice fed with a normal iodide diet (open squares) or with a low iodide diet (filled squares), obtained upon injection of 150 MBq of ^99mTcO₄ ⁻. The values presented are not corrected for decay. (C) Correspondence between thyroid activity (MBq) at 60 minutes post injection and absorbed dose to the thyroid (Gy) at 24 hours. (D) Absorbed dose to the thyroid at 24 hours in mice injected with 10 MBq (circles, n = 4), 25 MBq (triangles, n = 9), 100 MBq (squares, n = 9) or 150 MBq (diamonds, n = 29) ^99mTcO₄ ⁻.