Figure 4. Reduced trabecular bone mass in heterozygous and homozygous Akt1 deficient male mice.

A. Representative micro-CT images of the distal femoral metaphysis of male 20-week old mice with the indicated genotypes. B–E. Graphical presentation of data from 4–5 male mice for each indicated genotype (mean ± SEM; *- p≤0.01 vs. Akt1 WT). B. Trabecular thickness. C. Trabecular number. D. Trabecular spacing. E. BV/TV. Other statistical data are indicated.