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. 2014 Mar 24;9(3):e92993. doi: 10.1371/journal.pone.0092993

Figure 2. Screening of yeast deletion-mutants for NSNM sensitivity.

Figure 2

A–E) Growth Assay; yeast deletion mutants of various pathways were grown up to log phase. 3 μl of each undiluted and 10-fold serially diluted culture was spotted onto control SCA plates and SCA plates containing 100, 200 and 300 μM NSNM. All plates were incubated at 30°C for 72 h and photographed. Mutant yeast strains of A) Histone tails, B) HATs and HDACs, C) Molecular chaperones, D) Protein-ubiquitination pathways, E) TOR pathway.