Figure 2. Cortical hyper-excitability in corticobasal syndrome.

Patients with CBS had evidence of cortical hyper-excitability, with reduced SICI (A), significantly (P<0.05) reduced average SICI (B), and significantly (P<0.05) increased motor evoked potential – expressed as a ratio of compound motor action potential amplitude (C). Abbreviations: CBS  =  corticobasal syndrome, SICI  =  short-interval intracortical inhibition, MEP  =  motor evoked potential, CMAP  =  compound motor action potential.