Skip to main content
. 2014 Mar 24;9(3):e93072. doi: 10.1371/journal.pone.0093072

Figure 1. Deficiency in ST2 leads to pronounced microfilaremia and increased adult worm length.

Figure 1

A, microfilariae count per 50 μl of peripheral blood of ST2-ko mice and wild type (WT) controls throughout L. sigmodontis infection. B, microfilarial burden in the thoracic cavity 60 days post L. sigmodontis infection. C, percentage of ST2-ko mice and WT controls that develop patent infections. D, embryogram of female worms 60dpi (6 mice per group and two female worms per mouse). E, adult worm burden in ST2-ko mice and WT controls 35, 60 and 100 dpi, (F and G) length of male and female L. sigmodontis worms in WT and ST2-ko mice during infection. A and C show pooled data from three independent experiments with a minimum of 8 mice per group. B shows pooled data from two independent experiments and E-G show representative data of two independent experiments with a minimum of 6 mice per group. Differences were tested for statistical significance by Mann-Whitney-U-test, *p<0.05.