Skip to main content
. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Neurochem Res. 2013 Sep 24;39(6):1048–1056. doi: 10.1007/s11064-013-1148-3

Fig 1. The low dose effect of alphaxalone but not etomidate was absent in α4 KO mice.

Fig 1

a. Total distance traveled by WT and α4 KO mice in response to a low dose of alphaxalone (15 mg/kg) over a 10 min period. Genotypes did not differ in response to vehicle injection. Alphaxalone stimulated locomotor activity compared to vehicle in WT (p < 0.05) but not KO mice. b. Percent distance covered in the center zone of the open field by WT and α4 KO mice. No differences were observed between vehicle-treated and alphaxalone-treated WT and α4 KO animals. c. Total distance traveled in response to a low dose of etomidate (3 mg/kg). No differences were observed between WT and KO mice. Data are expressed as mean ± SEM.