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. Author manuscript; available in PMC: 2015 Feb 20.
Published in final edited form as: Immunity. 2014 Feb 6;40(2):262–273. doi: 10.1016/j.immuni.2014.01.003

Figure 1. Colonization of S. Typhimurium in WT and Il22−/− mice.

Figure 1

WT and Il22−/− mice were infected with S. Typhimurium and colony forming units (CFUs) in spleen (A) and colon content (B) were determined at 48h (WT n=10, Il22−/− n=10), 72h (WT n=11, Il22−/− n=9) and 96h (WT n=11, Il22−/− n=10) after infection. (C) Il22−/− mice were administered IL22-Fc or an isotype control antibody (n=3/group) and fecal samples were collected at 48h, 72h and 96h after infection. Data shown represent CFUs per mg of fecal material for colon content and CFUs per organ for spleen. Data represent the geometric mean ± standard error. n.s.= not significant. A significant decrease over WT control is indicated by ** (P value ≤ 0.01). (See also Fig. S1 and Table S1).