Table 2.

Characteristics and concomitant conditions that increase the risk of progression to diabetes

Characteristics and conditions

• Family history of diabetes

• Cardiovascular disease

• Excessive weight or obesity

• Sedentary lifestyle

• Non-white ancestry

• Previously identified IGT, IFG, HbA1c ≥5.7%, and/or metabolic syndrome

• Hypertension

• Increased levels of TG, low concentrations of HDL-C, or both

• History of gestational diabetes

• Delivery of a baby weighing >9 lb (4 kg)

• Polycystic ovary syndrome

• Antipsychotic therapy for schizophrenia and severe bipolar disorder

• Antidepressant therapy

• NODAT

• Intrauterine environment

Abbreviations: HbA_1c, glycated hemoglobin; HDL-C, high density lipoprotein cholesterol; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NODAT, new onset diabetes after transplant; TG, triglycerides.