Table S3.
Correlations between PIK3CA, NRAS, KIT mutations and clinicopathological characteristics of NPC patients
| Characteristics | PIK3CA
|
NRAS
|
KIT
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes | No | P-value | Yes | No | P-value | Yes | No | P-value | |
| Age (years) | 1.000 | 1.000 | 1.000 | ||||||
| <46 | 3 | 47 | 2 | 4 | 2 | 47 | |||
| ≥46 | 3 | 55 | 3 | 5 | 2 | 55 | |||
| Sex | 0.334 | 1.000 | 1.000 | ||||||
| Male | 6 | 78 | 4 | 7 | 3 | 78 | |||
| Female | 0 | 24 | 1 | 2 | 1 | 24 | |||
| Clinical stage | 0.333 | 0.611 | 1.000 | ||||||
| I+II | 0 | 27 | 2 | 2 | 1 | 27 | |||
| III+IV | 6 | 75 | 3 | 7 | 3 | 75 | |||
| Relapse/metastasis | 0.333 | 0.611 | 0.068 | ||||||
| No | 6 | 75 | 3 | 7 | 1 | 75 | |||
| Yes | 0 | 27 | 2 | 2 | 3 | 27 | |||
| WHO histological classification | 0.587 | 1.000 | 0.147 | ||||||
| NKUC | 6 | 85 | 4 | 8 | 2 | 85 | |||
| NKDC | 0 | 17 | 1 | 1 | 2 | 17 | |||
| KSCC | 0 | 0 | 0 | 0 | 0 | 0 | |||
Abbreviations: NPC, nasopharyngeal carcinoma; WHO, World Health Organization; NKUC, non-keratinizing undifferentiated carcinoma; NKDC, non-keratinizing differentiated carcinoma; KSCC, keratinizing squamous cell carcinoma.