Table 3.
Correlations between oncogene mutation and clinicopathological characteristics of NPC patients
| Characteristics | Mutation n=21 (17.1%) | Wild-type n=102 (82.9%) | P-value |
|---|---|---|---|
| Age (years) | 0.359 | ||
| <46 | 12 (20.3%) | 47 (79.7%) | |
| ≥46 | 9 (14.1%) | 55 (85.9%) | |
| Sex | 0.656 | ||
| Male | 17 (17.9%) | 78 (82.1%) | |
| Female | 4 (14.3%) | 24 (85.7%) | |
| Clinical stage | 0.800 | ||
| I+II | 5 (15.6%) | 27 (84.4%) | |
| III+IV | 16 (17.6%) | 75 (82.4%) | |
| Relapse/metastasis | 0.019 | ||
| No | 10 (11.8%) | 75 (88.2%) | |
| Yes | 11 (28.9%) | 27 (71.1%) | |
| WHO histological classification | 0.437 | ||
| NKUC | 16 (15.8%) | 85 (84.2%) | |
| NKDC | 5 (22.7%) | 17 (77.3%) | |
| KSCC | 0 (0%) | 0 (0%) |
Abbreviations: NPC, nasopharyngeal carcinoma; WHO, World Health Organization; NKUC, non-keratinizing undifferentiated carcinoma; NKDC, non-keratinizing differentiated carcinoma; KSCC, keratinizing squamous cell carcinoma.