Table 2.
Echocardiographic parameters at diagnosis as predictors of recovery (Left ventricular ejection fraction ≥ 50%) for peripartum cardiomyopathy n (%)
| Study | Recovered | Non-recovered | P |
| Goland et al[10,11] (25% African-American) | 115 (61.5) | 72 (38.5) | |
| Diagnosis mean LVEF | 0.31 | 0.23 | < 0.0001a |
| Diagnosis mean LVEDd (cm) | 5.5 | 6.1 | 0.002a |
| Amos et al[12] (51% African-American) | 22 (44.9) | 27 (55.1) | |
| Diagnosis mean LVEF | 0.23 | 0.20 | 0.16 |
| Mean LVEF (%) at 2 mo | 43 | 24 | < 0.001a |
| Diagnosis mean LVEDd (cm) | 5.6 | 6.2 | 0.01a |
| Modi et al[13] (88.6% African-American) | 14 (35) | 26 (65) | |
| Diagnosis mean LVEF | 0.29 | 0.21 | 0.02a |
| Diagnosis mean LVEDd (cm) | 5.9 | 6.2 | 0.16 |
| Fett et al[14] (all African heritage) | 32 (27.6) | 84 (72.4) | |
| Diagnosis mean LVEF | 0.28 | 0.23 | 0.002a |
| Diagnosis mean LVEDd (cm) | 5.6 | 5.9 | 0.03a |
| Safirstein et al[15] (3.6% African-American) | 43 (78.2) | 12 (21.8) | |
| Diagnosis mean LVEF | 0.29 | 0.24 | 0.13 |
| Diagnosis mean LVEDd (cm) | 5.4 | 5.9 | 0.21 |
| Diagnostic LVEF > 0.35 | 25/25 | 0 | < 0.001a |
| 1Haghikia et al[16] | 45 (47) | 51 (53) | |
| Diagnosis mean LVEF | 0.28 | 0.17 | < 0.0001a |
| McNamara et al[17] (30% African-American) | 59 (65) | 32 (35) | |
| Diagnostic LVEF < 0.30 | 10/30 (33) | 20/30 (67) | 0.001a |
| Diagnostic LVEF ≥ 0.30 | 58/70 (82.9)2 | 21/70 (17.1)2 | 0.001a |
1
For this group, recovery defined as LVEF 0.55, mean LVEF shown for improved vs non-improved;
2
Pending last echo late data entry from 12 mo postpartum. LVEDd: Left ventricular end-diastolic diameter; LVEF: Left ventricular ejection fraction; Recovered: Last LVEF ≥ 0.50; Non-recovered: Last LVEF < 0.50;
a
P ≤ 0.05 vs non-recovered.