. 2014 Feb 26;5(1):17–29. doi: 10.1007/s13193-014-0291-x

Table 4.

Risk levels for infertility promoted by various chemotherapeutic agents

Risk level	Risk due to nature or risks caused by nature of treatment of malignancy
High	Alkylating agents: cyclophosphamide, ifosfamide, chlormethine, busulfan, melphalan, chlorambucil, carmustine, lomustine, mechlorethamine; procarbazide
Medium	Cisplatin, carboplatin, doxorubicin
Low <20 %	Vincristine, methotrexate, dactinomycin, bleomycin, mercaptopurine, vinca alkaloids (vinblastine), fluorouracil
Risk exists unknown level	Nitrosources & antimetabolites: cytosine arabinoside
Unknown risk	Taxanes, oxaliplatin, monoclonal antibodies (trastuzumab, bevacizumab, cetuximab), tyrosine kinase inhibitors (eriotinib, imatinib)

Taken with kind permission from Ronit Abir

Cancer in Female Adolescents [31]. Elad Feigin, Ronit Abir, Fertility Preservation in Female Adolescents with Malignancies