Figure 4.

Comprehensive HDAC interaction network. Cytoscape interaction network representing 180 SAINT-filtered putative HDAC–prey interactions. HDAC–prey interactions were visualized by network edges. Preys were manually classified and color coded by biological processes. If known, preys were also grouped by subcomplex or function. Diamond and circle nodes indicate previously identified and uncharacterized HDAC interactions, respectively. Edge thickness indicates log₂-transformed prey spectral counts.