Table 1.
Surgery | Percutaneous ablative therapy | TACE | SBRT | |
Tumor size | < 5 cm (or more) | < 3 cm | > 3-5 cm | 4 (or 5) cm |
Number of tumors | < 3 | Depends on location | 1-multiple (> 4) | < 1-3 |
Location or characteristics | Depends on liver function | Away from large vessels or biliary system | Hypervascular lesions | Away from bowels |
Local control (2 yr) | > 90% | > 90% | < 65% | > 90% |
Level of evidence | High | Intermediate-high | Intermediate-high | Low |
Invasiveness | High | Less | Less | None |
Damage to the liver | High | Low | Low-moderate | Low-moderate |
SBRT: Stereotactic body radiation therapy; TACE: Transarterial chemoembolization.