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. 2014 Feb 15;4(5):475–486. doi: 10.7150/thno.7729

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Co-culture with BMSCs-ecSOD significantly promoted CMs survival and reduced ROS overproduction after H/SD injury. A: Cell viability measurement by MTT assay. B: Cell viability measurement by WST-8 assay. C: Representative images of immunostaining for apoptotic cells (green, TUNEL; blue, DAPI; scale bar, 100μm). D: Quantification of TUNEL assay. E: Caspase-3 activity assay. F: Representative images of DHE staining. G: Quantification of DHE staining. H: Analysis of O₂- production by lucigenin-enhanced chemiluminescence. *p < 0.05 vs. control group; ^#p< 0.05 vs. BMSC group; ^&p< 0.05 vs. BMSC-ecSOD group.